Doxazosin hydrochloride
| CAS No. | 70918-01-3 | Cat. No. | BCP13420 |
| Name | Doxazosin hydrochloride | ||
| Synonyms | UK 33274 HCl;UK33274 HCl;UK-33274 HCl;Doxazosin HCl; | ||
| Formula | C23H25N5O5.HCl | M. Wt | 487.94 |
| Description | Doxazosin is an α-1 adrenergic receptor blocker that inhibits the binding of norepinephrine, which is released from sympathetic nerve terminals, to the α-1 receptors on the membrane of vascular smooth muscle cells. Blockages of the alpha-1 adrenergic action on the vascular smooth muscles lead to a decrease in vascular resistance and antihypertensive activity. This agent also shows high affinity to alpha-1c adrenoceptor, the predominant functional type in the prostate, which may partially attribute to its effect in treatment of benign prostatic hyperplasia. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | Adrenergic Receptor | ||
Structure
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