JNK-IN-7
CAS No. | 1408064-71-0 | Cat. No. | BCP13495 |
Name | JNK-IN-7 | ||
Synonyms | JNK inhibitor; | ||
Formula | C28H27N7O2 | M. Wt | 493.56 |
Description | Covalent modification of IRAK1 by JNK-IN-7 is a possibility and subsequent biochemical kinase assay revealed anIC50 of ~10 nM against IRAK1. JNK-IN-7 exhibited binding inhibition of 95% or more to approximately 14 kinases at the concentration of 1.0 μM. JNK-IN-7 was next tested for its ability to inhibit the enzymatic activity of a panel of 121 kinases at a concentration of 1.0 μM . | ||
Pathways | MAPK Pathway | ||
Targets | JNK |
Structure
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