JNK-IN-7

  • Chemical Properties
CAS No. 1408064-71-0 Cat. No. BCP13495
Name JNK-IN-7
Synonyms JNK inhibitor;
Formula C28H27N7O2 M. Wt 493.56
  • Biological Activity
Description Covalent modification of IRAK1 by JNK-IN-7 is a possibility and subsequent biochemical kinase assay revealed anIC50 of ~10 nM against IRAK1. JNK-IN-7 exhibited binding inhibition of 95% or more to approximately 14 kinases at the concentration of 1.0 μM. JNK-IN-7 was next tested for its ability to inhibit the enzymatic activity of a panel of 121 kinases at a concentration of 1.0 μM .
Pathways MAPK Pathway 
Targets JNK 

Structure

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