Diphenhydramine hydrochloride

CAS No.	147-24-0	Cat. No.	BCP13546
Name	Diphenhydramine hydrochloride
Synonyms	DPH;Benadryl;
Formula	C17H22ClNO	M. Wt	291.82

Description	Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Histamine Receptor

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