E-64 Protease Inhibitor

  • Chemical Properties
CAS No. 66701-25-5 Cat. No. BCP13591
Name E-64 Protease Inhibitor
Synonyms Proteinase inhibitor E 64;E-64; E 64; E64;Trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane;N-(trans-Epoxysuccinyl)-L-leucine 4-guanidinobutylamide;
Formula C15H27N5O5 M. Wt 357.41
  • Biological Activity
Description E-64 is a potent, and irreversible inhibitor of cysteine proteases with IC50 values for inhibiting cathepsins K, S, and L, in vitro, are 1.4, 4.1, and 2.5 nM, respectively. E-64 improves the preimplantation development of bovine somatic cell nuclear transfer embryos.
Pathways Protease/Metabolic Enzyme 
Targets Cathepsin 

Structure

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