Z-JIB-04
| CAS No. | 199596-24-2 | Cat. No. | BCP13580 |
| Name | Z-JIB-04 | ||
| Synonyms | JIB-04 Z-isomer;NSC 693627;NSC-693627;NSC693627; | ||
| Formula | C17H13ClN4 | M. Wt | 308.76 |
| Description | JIB-04 Z-isomer, also known as NSC 693627, is an isomer of JIB-04. JIB-04 is a Jumonji histone demethylase inhibitor. JIB-04 selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo. JIB-04 can prolong survival in a mouse model of breast cancer. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Demethylase | ||
Structure
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