ICA-121431
| CAS No. | 313254-51-2 | Cat. No. | BCP28611 |
| Name | ICA-121431 | ||
| Synonyms | ICA 121431; ICA121431; | ||
| Formula | C23H19N3O3S2 | M. Wt | 449.55 |
| Description | ICA-121431 is a potent, selective inhibitor of the human Nav1.3 and Nav1.1 voltage gated sodium channels (IC50 = 19 nM) with little or no activity against human Nav1.5 or Nav1.7 channels. Voltage-gated sodium channels initiate action potentials in brain neurons, and sodium channel blockers are used in therapy of epilepsy. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Sodium Channel | ||
Structure
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