L-Norepinephrine bitartrate

  • Chemical Properties
CAS No. 108341-18-0 Cat. No. BCP13659
Name L-Norepinephrine bitartrate
Synonyms L-Norepinephrine bitartrate hydride;Norepinephrine bitartrate monohydrate;Noradrenaline bitartrate monohydrate;
Formula C12H17NO9.H2O M. Wt 337.28
  • Biological Activity
Description Norepinephrine bitartrate monohydrate is a β1-selective adrenergic receptor agonist with EC50 of 5.37 μM.Norepinephrine is an organic chemical in the catecholamine family that functions in the human brain and body as a hormone and neurotransmitter. Norepinephrine directly stimulates adrenergic receptors. Stimulation of alpha-adrenergic receptors causes vasoconstriction of the radial smooth muscle of the iris, arteries, arterioles, veins, urinary bladder, and the sphincter of the gastrointestinal tract. Stimulation of beta-1 adrenergic receptors causes an increase in myocardial contractility, heart rate, automaticity, and atrioventricular (AV) conduction while stimulation of beta-2 adrenergic receptors causes bronchiolar and vascular smooth muscle dilatation.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Adrenergic Receptor 

Structure

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