Methotrexate hydrate
CAS No. | 133073-73-1 | Cat. No. | BCP13701 |
Name | Methotrexate hydrate | ||
Synonyms | |||
Formula | C20H22N8O5 | M. Wt | 454.44 |
Description | Methotrexate ,analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. | ||
Pathways | Cell Cycle/DNA Damage Others Pathway | ||
Targets | ADC Related DHFR |
Structure
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