Methotrexate hydrate

  • Chemical Properties
CAS No. 133073-73-1 Cat. No. BCP13701
Name Methotrexate hydrate
Synonyms
Formula C20H22N8O5 M. Wt 454.44
  • Biological Activity
Description Methotrexate ,analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH.
Pathways Cell Cycle/DNA Damage Others Pathway 
Targets ADC Related DHFR 

Structure

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