Methotrexate disodium salt
CAS No. | 7413-34-5 | Cat. No. | BCP13700 |
Name | Methotrexate disodium salt | ||
Synonyms | Methotrexate disodium; MTX sodium;Sodium methotrexate; | ||
Formula | C20H20N8Na2O5 | M. Wt | 498.4 |
Description | Methotrexate Sodium is the sodium salt of methotrexate, an antimetabolite with antineoplastic and immunomodulating properties. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant properties. | ||
Pathways | Cell Cycle/DNA Damage Others Pathway | ||
Targets | ADC Related DHFR |
Structure
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