Levamisole hydrochloride

  • Chemical Properties
CAS No. 16595-80-5 Cat. No. BCP13755
Name Levamisole hydrochloride
Synonyms ((-)-Tetramisole hydrochloride;Ergamisol;
Formula C11H13ClN2S M. Wt 240.75
  • Biological Activity
Description Levamisole suppresses the production of white blood cells, resulting in neutropenia and agranulocytosis. With the increasing use of levamisole as an adulterant, a number of these complications have been reported among cocaine users . Levamisole reversibly and noncompetitively inhibits most isoforms of alkaline phosphatase (e.g., human liver, bone, kidney, and spleen) except the intestinal and placental isoform . It is thus used as an inhibitor along with substrate to reduce background alkaline phosphatase activity in biomedical assays involving detection signal amplification by intestinal alkaline phosphatase, for example in in situ hybridization or Western blot protocols. It is used to immobilize the nematode C. elegans on glass slides for imaging.
Pathways Microbiology/Virology 
Targets Antiparasitics 

Structure

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