Suramin sodium
| CAS No. | 129-46-4 | Cat. No. | BCP13783 |
| Name | Suramin sodium | ||
| Synonyms | Suramin hexasodium salt; BAY-205; NF-060;Suramin sodium salt; NSC-34936l; NSC34936 ; NSC 34936; | ||
| Formula | C51H34N6Na6O23S6 | M. Wt | 1429.17 |
| Description | Suramin sodium salt is a polysulfonated naphthylurea that inhibits the binding of calmodulin to recognition sites on the ryanodine receptor-1 (IC50 = 4.9 μM), blocks G protein coupling to GPCRs, and non-selectively antagonizes P2 purinergic receptors (10-100 μM). | ||
| Pathways | Ion Channel/Membrane Transporter Protease/Metabolic Enzyme Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | E1 E2 E3 Enzyme P2 Receptor | ||
Structure
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