Benserazide hydrochloride

  • Chemical Properties
CAS No. 14919-77-8 Cat. No. BCP14068
Name Benserazide hydrochloride
Synonyms Benserazide HCl; 2'-(2,3,4-Trihydroxybenzyl)-DL-serinohydrazide monohydrochloride;
Formula C10H15N3O5.HCl M. Wt 293.71
  • Biological Activity
Description Benserazide is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor. It inhibits this decarboxylation, and since it itself cannot cross the blood-brain barrier, this allows dopamine to build up solely in the brain instead. Adverse effects caused by peripheral dopamine, such as nausea and arrhythmia, are minimized. However, benserazide cannot reduce the centrally-mediated side effects of levodopa, particularly dyskinesia.
Pathways Others Pathway 
Targets Others 

Structure

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