Lubiprostone
| CAS No. | 136790-76-6 | Cat. No. | BCP14113 |
| Name | Lubiprostone | ||
| Synonyms | Amitiza;RU-0211;SPI-0211;RU0211;SPI0211;RU 0211;SPI 0211; | ||
| Formula | C20H32F2O5 | M. Wt | 390.46 |
| Description | Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Chloride Channel | ||
Structure
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