Pinometostat
| CAS No. | 1380288-88-9 | Cat. No. | BCP14198 |
| Name | Pinometostat | ||
| Synonyms | EPZ-5676;EPZ5676;Pinometostat; | ||
| Formula | C30H42N8O3 | M. Wt | 562.71 |
| Description | EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase with Ki of < 80 pM, demonstrating > 37,000-fold selectivity against all other PMTs tested, and inhibits H3K79 methylation in tumor. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Methyltransferase | ||
Structure
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