LY3000328

  • Chemical Properties
CAS No. 1373215-15-6 Cat. No. BCP14297
Name LY3000328
Synonyms Z-FL-COCHO;Cathepsin S inhibitor; LY-3000328; LY 3000328;
Formula C24H30N2O6 M. Wt 442.5
  • Biological Activity
Description LY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA.
Pathways Protease/Metabolic Enzyme 
Targets Cathepsin 

Structure

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