Indirubin-3
| CAS No. | 160807-49-8 | Cat. No. | BCP14390 |
| Name | Indirubin-3 | ||
| Synonyms | Indirubin-3-monoxime;Indirubin-3-oxime; | ||
| Formula | C16H11N3O2 | M. Wt | 277.28 |
| Description | Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and a less potent inhibitor of 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM. | ||
| Pathways | Protease/Metabolic Enzyme Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | Lipoxygenase GSK3 | ||
Structure
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