HTH-01-015
| CAS No. | 1613724-42-7 | Cat. No. | BCP14400 |
| Name | HTH-01-015 | ||
| Synonyms | HTH 01 015; | ||
| Formula | C26H28N8O | M. Wt | 468.55 |
| Description | HTH-01-015 did not markedly suppress the activity of any of the other 139 protein kinases evaluated. Treatment of cells with 10 μM HTH-01-015, the NUAK1 isoform selective inhibitor, only led to a partial inhibition of MYPT1 phosphorylation. In HEK-293 cells expressing wild-type NUAK1, concentrations of 3–10 μM WZ4003 or HTH-01-015 markedly suppressed phosphorylation of MYPT1. | ||
| Pathways | PI3K/Akt/mTOR Epigenetics | ||
| Targets | AMPK | ||
Structure
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