MG 149
| CAS No. | 1243583-85-8 | Cat. No. | BCP14627 |
| Name | MG 149 | ||
| Synonyms | MG149;MG-149; | ||
| Formula | C22H28O3 | M. Wt | 340.45 |
| Description | MG 149, at 200 μM, inhibited about 90% of Tip60 activity but had no inhibitory impact on p300 and PCAF. MG 149 was essentially competitive with Ac-CoA and noncompetitive with the histone substrate. HAT inhibition studies with MG 149 demonstrated that both compounds inhibited the HAT activity of the nuclear extracts. | ||
| Pathways | Epigenetics | ||
| Targets | Histone Acetyltransferase Epigenetic Reader Domain | ||
Structure
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