T-5224

  • Chemical Properties
CAS No. 530141-72-1 Cat. No. BCP14701
Name T-5224
Synonyms T 5224;T5224;
Formula C29H27NO8 M. Wt 517.53
  • Biological Activity
Description T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation.
Pathways Protease/Metabolic Enzyme 
Targets MMP 

Structure

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