Cariprazine
CAS No. | 839712-12-8 | Cat. No. | BCP14691 |
Name | Cariprazine | ||
Synonyms | RGH-188; RGH188; RGH 188; MP-214; MP 214; MP214; | ||
Formula | C21H32Cl2N4O | M. Wt | 427.41 |
Description | Cariprazine, also known as RGH-188 and MP-214, is an antipsychotic drug received FDA approval on September 17, 2015. Cariprazine acts as a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor. Action on the dopaminergic systems makes it also potentially useful as an add-on therapy in major depressive disorder. Cariprazine is approved for schizophrenia and bipolar disorder. It has also been investigated as a potential adjunct in treatment-resistant major depressive disorder. | ||
Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
Targets | Dopamine Receptor |
Structure
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