PIK-75 Hydrochloride
| CAS No. | 372196-77-5 | Cat. No. | BCP14766 |
| Name | PIK-75 Hydrochloride | ||
| Synonyms | PIK 75 Hydrochloride;PIK75 Hydrochloride; | ||
| Formula | C16H14BrN5O4S.HCl | M. Wt | 488.74 |
| Description | PIK-75 is a DNA-PK and PI3K inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC50=1.3 μM). | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR | ||
| Targets | DNA PK PI3K | ||
Structure
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