PF-06447475
| CAS号 | 1527473-33-1 | 货号 | BCP14890 |
| 中文名 | PF-06447475 | ||
| 英文名 | PF-06447475 | ||
| 中文别名 | |||
| 英文别名 | PF06447475;PF 06447475; | ||
| 分子式 | C17H15N5O | 分子量 | 305.33 |
| 生物活性 | PF-06447475 was sufficiently potent in the LRRK2 whole cell assay (WCA; IC50=25 nM) (pS935 end point) to warrant additional profiling. Oral administration of PF-06447475 twice daily for 15 days was well tolerated at doses up to 60 mg kg-1 day-1 (31-fold Cave,0.24h; 70-fold Cmax) with only minimal alterations in RBC parameters, electrolytes, and food consumption without concurrent effects on body weight. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | LRRK2 | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！