马来酸乙巯拉嗪
| CAS号 | 1179-69-7 | 货号 | BCP15054 |
| 中文名 | 马来酸乙巯拉嗪 | ||
| 英文名 | Thiethylperazine Maleate | ||
| 中文别名 | |||
| 英文别名 | Torecan maleate; | ||
| 分子式 | C30H37N3O8S2 | 分子量 | 631.76 |
| 生物活性 | Thiethylperazine Maleate is the maleate salt form of triethylperazine, a piperazine phenothiazine derivative and a dopamine antagonist used as antiemetic. Thiethylperazine blocks postsynaptic dopamine 2 (D2) receptors in the medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain. Peripherally, thiethylperazine blocks the vagus nerve in the gastrointestinal tract. In addition, this agent also shows antagonistic activities mediated through muscarinic receptors, H1-receptors, and alpha(1)-receptors. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Dopamine Receptor | ||
结构式
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