Volitinib
| CAS No. | 1313725-88-0 | Cat. No. | BCP15079 |
| Name | Volitinib | ||
| Synonyms | Savolitinib; HMPL 504; HMPL0-504; HMPL504; AZD 6094; AZD 6094; AZD-6094; | ||
| Formula | C17H15N9 | M. Wt | 345.36 |
| Description | Savolitinib, also known as Volitinib, AZD6094 or HMPL-504, is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c-Met protein. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | c Met | ||
Structure
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