SKQ1

  • Chemical Properties
CAS No. 934826-68-3 Cat. No. BCP15201
Name SKQ1
Synonyms SKQ-1;SKQ 1;Visomitin; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide;
Formula C36H42BrO2P M. Wt 617.6
  • Biological Activity
Description SKQ1, also known as Visomitin, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API for making eye drop drug called Visomitin. SKQ1 showed activities (1) to prevent amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices; (2) to reverse aging-related biomarkers in rats; (3) to slow down the development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats; (4) to increase the lifespan of male rodents under LP or SPF conditions. SKQ1 can penetrate cell membranes , and is proposed as an anti-aging treatment. Visomitin, which API is SKQ1, is currently under clinical trials for treating glaucoma in Russia. Note: For the convenience of use, SKQ1 is supplied as solution of 200mg / mL in ethanol-water (1:1, v/v).
Pathways Others Pathway 
Targets Others 

Structure

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