Anamorelin hydrochloride

  • Chemical Properties
CAS No. 861998-00-7 Cat. No. BCP15207
Name Anamorelin hydrochloride
Synonyms RC-1291 hydrochloride;ONO-7643 hydrochloride;RC1291 hydrochloride;ONO7643 hydrochloride;RC 1291 hydrochloride;ONO 7643 hydrochloride;
Formula C31H43ClN6O3 M. Wt 583.16
  • Biological Activity
Description Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.
Pathways GPCR/G Protein 
Targets GHSR 

Structure

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