FG2216
| CAS No. | 223387-75-5 | Cat. No. | BCP15220 |
| Name | FG2216 | ||
| Synonyms | FG-2216;FG 2216;YM311; YM-311; YM 311; | ||
| Formula | C12H11ClN2O3 | M. Wt | 266.68 |
| Description | FG-2216, also known as YM311, is orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. FG-2216 showed the ability to stabilize HIF-α, to stimulate EPO secretion in in vitro studies, and to increase hematocrit, red blood cell count, and hemoglobin levels in an animal efficacy study. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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