Lifitegrast
| CAS No. | 1025967-78-5 | Cat. No. | BCP15239 |
| Name | Lifitegrast | ||
| Synonyms | SAR-1118; SAR 1118; SAR1118; | ||
| Formula | C29H24Cl2N2O7S | M. Wt | 615.48 |
| Description | Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Lifitegrast inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | Integrin | ||
Structure
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