Migalasta
| CAS No. | 108147-54-2 | Cat. No. | BCP15236 |
| Name | Migalasta | ||
| Synonyms | AT1001; AT 1001; AT-1001; GR181413A; GR 181413A; GR-181413A; 1-deoxygalactonojirimycin; | ||
| Formula | C6H13NO4 | M. Wt | 163.17 |
| Description | Migalastat is a potent, orally available inhibitor of α-GalA (IC50: 4 μM).[4] When binding to faulty α-GalA, it shifts the folding behaviour towards the proper conformation, resulting in a functional enzyme provided the mutation is amenable.Molecules with this type of mechanism are called pharmacological chaperones. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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