Torezolid Phosphate Disodium

CAS No.	856867-39-5	Cat. No.	BCP15351
Name	Torezolid Phosphate Disodium
Synonyms	Tedizolid phosphate disodium salt;DA 7218; TR 701;DA7218; TR701;DA-7218; TR-701;
Formula	C17H16FN6Na2O7P	M. Wt	494.29

Description	Tedizolid phosphate is a novel antibacterial prodrug with potent activity against Gram-positive pathogens. In vitro and in vivo studies demonstrated that the prodrug is rapidly converted by nonspecific phosphatases to the biologically active moiety tedizolid. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp. Tedizolid has consistently shown potency advantages over linezolid against Gram-positive microorganisms including those with reduced susceptibility to linezolid. Of particular significance, minimum inhibitory concentrations of tedizolid appear to be largely unaffected by the chloramphenicol-florfenicol resistance (cfr) gene, which has been implicated in a number of published linezolid-resistant organism outbreaks.
Pathways	Microbiology/Virology
Targets	Antibiotic

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