Phthalic acid

CAS No.	88-99-3	Cat. No.	BCP15370
Name	Phthalic acid
Synonyms	O-phthalic acid; Pathalic acid;
Formula	C8H6O4	M. Wt	166.13

Description	Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(COOH)2. Phthalic acid is used mainly in the form of the anhydride to produce other chemicals such as dyes, perfumes, saccharin, phthalates and many other useful products. Phthalic acid, when found in tissues or biofluids arises from exposure to these phthalate products. Phthalate is an environmental chemical of heightened public concern because reports of its potential risk to male reproductive health (PMID: 16804814), being significantly associated with reduced sperm concentration to pesticide concentration in men's urine (PMID: 16804812). Within the reproductive tract, the male is exquisitely vulnerable to the effects of anti-androgens during development due the reliance on the synthesis and action of androgens for the masculinization of the male reproductive tract. The ability of phthalates to suppress androgen synthesis during development and to induce testicular dysgenesis together with cryptorchidism and hypospadias has raised considerable concern.
Pathways	Others Pathway
Targets	Others

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