N-Desmethyl Zolmitriptan

CAS No.	139264-35-0	Cat. No.	BCP15367
Name	N-Desmethyl Zolmitriptan
Synonyms	Zolmitriptan USP Related Compound A;
Formula	C15H19N3O2	M. Wt	273.34

Description	N-Desmethyl Zolmitriptan is one of the impurities of Zolmitriptan.Zolmitriptan is a member of the triptan class agents with anti-migraine property. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B expressed in intracranial arteries and 5_HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels, reduction of the vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relief migraine headaches by inhibition pro-inflammatory neuropeptide release.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	5 HT Receptor/Serotonin Receptor

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