MIF Antagonist, ISO-1
| CAS No. | 478336-92-4 | Cat. No. | BCP15471 |
| Name | MIF Antagonist, ISO-1 | ||
| Synonyms | ISO-1; ISO 1; ISO1; MIF Antagonist; Macrophage Migration Inhibitory Factor; | ||
| Formula | C12H13NO4 | M. Wt | 235.24 |
| Description | ISO-1, also known as MIF Antagonist , is a MIF inhibitor. MDK-6924 Protects Photoreceptors and Reduces Gliosis in Experimental Retinal Detachment. Systemic administration of the MIF inhibitor ISO-1 significantly blocked photoreceptor apoptosis, outer nuclear layer (ONL) thinning, and retinal gliosis. ISO-1 and MIF knockout (MIFKO) had greater accumulation of Müller glia pERK expression in the detached retina, suggesting that Müller survival pathways might underlie the neuroprotective response. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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