Ruxolitinib S enantiomer
| CAS No. | 941685-37-6 | Cat. No. | BCP15524 |
| Name | Ruxolitinib S enantiomer | ||
| Synonyms | S-Ruxolitinib;S-INCB18424;INCB-18424;INCB18424;INCB 18424; | ||
| Formula | C17H18N6 | M. Wt | 306.37 |
| Description | S-Ruxolitinib is S enantiomer of Ruxolitinib; Ruxolitinib(INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | JAK | ||
Structure
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