H-89 Dihydrochloride
CAS No. | 130964-39-5 | Cat. No. | BCP15626 |
Name | H-89 Dihydrochloride | ||
Synonyms | Protein kinase inhibitor H-89 dihydrochloride;H-89; H89; H 89 2HCl; | ||
Formula | C20H22BrCl2N3O2S | M. Wt | 519.28 |
Description | H-89 is a specific adenylyl cyclase inhibitor (DDA) and a cyclic AMP-dependent protein kinase inhibitor. H-89 blocks the action of equine growth hormone on in vitro maturation of equine oocytes. H-89 decreases the gain of excitation-contraction coupling and attenuates calcium sparks in the absence of beta-adrenergic stimulation. H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A. | ||
Pathways | GPCR/G Protein Wnt/Stem Cell | ||
Targets | PKA |
Structure
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