Cynaropicrin
| CAS No. | 35730-78-0 | Cat. No. | BCP15633 |
| Name | Cynaropicrin | ||
| Synonyms | |||
| Formula | C19H22O6 | M. Wt | 346.38 |
| Description | Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling. | ||
| Pathways | Protease/Metabolic Enzyme Apoptosis Pathway NFκB | ||
| Targets | TNF Receptor NF κB MMP | ||
Structure
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