ONO-4059 analog
| CAS No. | 1351635-67-0 | Cat. No. | BCP15643 |
| Name | ONO-4059 analog | ||
| Synonyms | ONO 4059 analog;ONO4059 analog; | ||
| Formula | C25H24N6O3 | M. Wt | 456.5 |
| Description | in vitro: ONO-4059 ( analog ) is a selective, once-daily, oral inhibitor of BTK, which has been shown to play a role in the survival and proliferation of malignant B-cells. ONO-4059 (analog) shows a favourable safety profile along with promising efficacy in this difficult-to-treat patient population. in vivo: ONO-4059 (analog) has demonstrated anti-tumour activity in several pre-clinical models. ONO-4059 (analog) potently and dose-dependently reverse clinical arthritis and prevented bone damage in the CIA model. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | BTK | ||
Structure
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