Apilimod dimesylate
| CAS No. | 870087-36-8 | Cat. No. | BCP15711 |
| Name | Apilimod dimesylate | ||
| Synonyms | STA 5326 mesylate;STA-5326 mesylate;STA5326 mesylate; AIT-101 mesylate; | ||
| Formula | C25H34N6O8S2 | M. Wt | 610.7 |
| Description | Apilimod mesylate is a potent and orally-available inhibitor of the cytokines interleukin-12 (IL-12) and interleukin-23 (IL-23) with the potential to treat certain autoimmune and inflammatory diseases. Apilimod mesylate (STA-5326 mesylate) inhibits IL-12 with IC50 of 1 nM, 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs, human monocytes and mouse PBMCs, respectively. Apilimod mesylate (STA-5326 mesylate) is also a cell permeable small molecule that specifically inhibits PIKfyve with IC50 of 14 nM. | ||
| Pathways | Others Pathway | ||
| Targets | Interleukin Related | ||
Structure
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