FLT3-IN-1
| CAS No. | 1370256-78-2 | Cat. No. | BCP15716 |
| Name | FLT3-IN-1 | ||
| Synonyms | FLT3-IN1;FLT3IN1;SKLB4771; SKLB-4771; SKLB 4771; | ||
| Formula | C25H27N7O3S2 | M. Wt | 537.66 |
| Description | FLT3-IN-1, also known as SKLB4771, is a potent and selective FLT3 inhibitor potentially for the treatment of cutaneous inflammation and psoriasis-like symptoms of disease. Mechanistic studies indicated that SKLB4771 treatment significantly decreased the number and activation of pDCs and mDCs in vitro and in vivo, and subsequent T-cell cascade reactions mediated by Th1/Th17 pathways. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FLT3 | ||
Structure
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