维罗司他
CAS号 | 1286770-55-5 | 货号 | BCP15722 |
中文名 | 维罗司他 | ||
英文名 | Verubecestat | ||
中文别名 | |||
英文别名 | MK 8931;MK-8931;SCH 900931;SCH900931;SCH-900931;MK8931; | ||
分子式 | C17H17F2N5O3S | 分子量 | 409.41 |
生物活性 | MK-8931, also known as Verubecestat or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. | ||
信号通路 | Neuro Signaling Pathway | ||
靶 点 | Beta secretase |
结构式
![](https://img.biochemsafebuy.com/uploads/img/1286770-55-5_BCP15722.png)
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