ELN 441958

  • Chemical Properties
CAS No. 913064-47-8 Cat. No. BCP23812
Name ELN 441958
Synonyms ELN441958; ELN-441958;
Formula C29H29ClN4O2 M. Wt 501.03
  • Biological Activity
Description ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958 is highly selective for B1 over B2 receptors, and >500/ 2000-fold selective for the B1 over μ/δ-opioid receptor.
Pathways GPCR/G Protein 
Targets Bradykinin Receptor 

Structure

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