ELN 441958
CAS No. | 913064-47-8 | Cat. No. | BCP23812 |
Name | ELN 441958 | ||
Synonyms | ELN441958; ELN-441958; | ||
Formula | C29H29ClN4O2 | M. Wt | 501.03 |
Description | ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958 is highly selective for B1 over B2 receptors, and >500/ 2000-fold selective for the B1 over μ/δ-opioid receptor. | ||
Pathways | GPCR/G Protein | ||
Targets | Bradykinin Receptor |
Structure
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