Casin

  • Chemical Properties
CAS No. 425399-05-9 Cat. No. BCP15785
Name Casin
Synonyms CASIN;
Formula C20H22N2O M. Wt 306.4
  • Biological Activity
Description CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo.
Pathways GPCR/G Protein 
Targets Ras/Rho 

Structure

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