Fexaramine
| CAS号 | 574013-66-4 | 货号 | BCP15784 |
| 中文名 | Fexaramine | ||
| 英文名 | Fexaramine | ||
| 中文别名 | |||
| 英文别名 | |||
| 分子式 | C32H36N2O3 | 分子量 | 496.65 |
| 生物活性 | Fexaramine is an agonist of the farnesoid X receptor (FXR), which is a bile acid-activated nuclear receptor that controls bile-acid synthesis, conjugation and transport, as well as lipid metabolism through actions in the liver and intestine. Fexaramine has 100-fold greater affinity for FXR than natural compounds and described the genomic targets and binding site on FXR. When administered orally to mice, fexaramine produced selective actions through FXR receptors in the intestines. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | FXR | ||
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Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
购于瀚香生物(Biochempartner)的Fexaramine(CAS:574013-66-4)被引用 |
结构式
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