Inecalcitol
| CAS No. | 163217-09-2 | Cat. No. | BCP23832 |
| Name | Inecalcitol | ||
| Synonyms | TX-522; TX 522; TX522; | ||
| Formula | C26H40O3 | M. Wt | 400.59 |
| Description | Inecalcitol is an analog of calcitriol and a vitamin D3 receptor (VDR) agonist, with potential antineoplastic activity. Upon administration, inecalcitol targets and binds to VDR. This activates VDR and VDR-mediated signal transduction pathways. This modulates the VDR-mediated expression of certain genes, including the expression of anti-cancer genes, enhances cellular differentiation, induces tumor cell apoptosis and inhibits tumor cell growth. VDR plays a central role in calcium homeostasis and in the growth of certain cancer cells. | ||
| Pathways | Others Pathway | ||
| Targets | Vitamin D Related | ||
Structure
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