伊奈骨化醇
| CAS号 | 163217-09-2 | 货号 | BCP23832 |
| 中文名 | 伊奈骨化醇 | ||
| 英文名 | Inecalcitol | ||
| 中文别名 | 依奈骨化醇; | ||
| 英文别名 | TX-522; TX 522; TX522; | ||
| 分子式 | C26H40O3 | 分子量 | 400.59 |
| 生物活性 | Inecalcitol is an analog of calcitriol and a vitamin D3 receptor (VDR) agonist, with potential antineoplastic activity. Upon administration, inecalcitol targets and binds to VDR. This activates VDR and VDR-mediated signal transduction pathways. This modulates the VDR-mediated expression of certain genes, including the expression of anti-cancer genes, enhances cellular differentiation, induces tumor cell apoptosis and inhibits tumor cell growth. VDR plays a central role in calcium homeostasis and in the growth of certain cancer cells. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Vitamin D Related | ||
结构式
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