Sacubitril Sodium Salt
| CAS No. | 149690-05-1 | Cat. No. | BCP15909 |
| Name | Sacubitril Sodium Salt | ||
| Synonyms | Sacubitril sodium;AHU337; AHU-337; AHU 337; LCZ696; LCZ 696; LCZ696; | ||
| Formula | C24H28NNaO5 | M. Wt | 433.47 |
| Description | Sacubitril is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. | ||
| Pathways | Protease/Metabolic Enzyme GPCR/G Protein | ||
| Targets | Angiotensin Receptor Neprilysin | ||
Structure
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