CC122
| CAS No. | 1015474-32-4 | Cat. No. | BCP15938 |
| Name | CC122 | ||
| Synonyms | CC-122;CC 122;Avadomide; | ||
| Formula | C14H14N4O3 | M. Wt | 286.29 |
| Description | CC-122 is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Aiolos and Ikaros in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | E1 E2 E3 Enzyme | ||
Structure
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