Darolutamide
| CAS No. | 1297538-32-9 | Cat. No. | BCP15972 |
| Name | Darolutamide | ||
| Synonyms | ODM201;ODM 201;ODM-201; BAY-1841788; BAY1841788; BAY 1841788; | ||
| Formula | C19H19ClN6O2 | M. Wt | 398.85 |
| Description | Darolutamide is a formulation containing an androgen receptor (AR) antagonist with potential antineoplastic activity. Darolutamide binds to ARs in target tissues; subsequently, inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. This prevents binding to and transcription of AR-responsive genes that regulate prostate cancer cell proliferation. This ultimately leads to an inhibition of growth in AR-expressing prostate cancer cells. | ||
| Pathways | Hormone Pathay | ||
| Targets | Androgen Receptor | ||
Structure
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