RO8994

  • Chemical Properties
CAS No. 1309684-94-3 Cat. No. BCP15973
Name RO8994
Synonyms RO-8994;RO 8994;
Formula C31H31Cl2FN4O4 M. Wt 613.51
  • Biological Activity
Description RO8994 is a highly potent and selective series of spiroindolinone small-molecule MDM2 inhibitor, with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays).
Pathways Apoptosis Pathway 
Targets Mdm2 

Structure

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