AMG-925
| CAS No. | 1401033-86-0 | Cat. No. | BCP15977 |
| Name | AMG-925 | ||
| Synonyms | AMG925;AMG 925;FLX925; FLX-925; FLX 925.; | ||
| Formula | C26H29N7O2 | M. Wt | 471.55 |
| Description | AMG 925 is a potent and selective dual inhibtor of CDK4/FLT3 with IC50s of 1.5 nM and 2.4 nM for CDK4 and FLT3, respectively; with IC50 of 19 nM in MOLM-13 cell. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Cell Cycle/DNA Damage | ||
| Targets | FLT3 CDK | ||
Structure
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